Dynamin 1 anticorps (Middle Region)

N° du produit ABIN630914

L’anticorps Lapin Polyclonal anti-Dynamin 1 a été validé pour WB. Il convient pour détecter Dynamin 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Dynamin 1 anticorps (Middle Region) (ABIN630914)

Antigène: Dynamin 1 (DNM1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Dynamin 1 anticorps

Épitope: Middle Region

Specificité: Dynamin 1 antibody was raised against the middle region of DNM1

Purification: Affinity purified

Immunogène: Dynamin 1 antibody was raised using the middle region of DNM1 corresponding to a region with amino acids PPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPA

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Dynamin 1 Blocking Peptide, (ABIN5613275), is also available for use as a blocking control in assays to test for specificity of this Dynamin 1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DNM1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur Dynamin 1

Antigène: Dynamin 1 (DNM1)

Autre désignation: Dynamin 1

Sujet: DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 95 kDa (MW of target protein)

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling